Largest clinical study ever reveals this app is more effective than the pill and other fertility awareness based methods

Hi there,   Hope all's good.   The largest clinical study ever conducted on the effectiveness of Fertility Awareness Based (FAB) methods (also called natural family planning) has concluded that Natural Cycles, the first app to be certified as a contraception, is more effective than traditional FAB methods and comparable to the contraceptive pill.   Details and imagery below. Do let me know if you can run this.   Thanks, Harry   Harry Cymbler Founder T: 020 7607 2413 M: 07801 289 996 www.hotcherry.co.uk   Largest ever study demonstrates effectiveness of contraception app       The largest prospective observational study* ever performed on the effectiveness of Fertility Awareness Based (FAB) methods (also called natural family planning) has concluded that Natural Cycles, the first app to be certified as a contraception in the EU, provides an effective alternative for women who are looking for non-hormonal options, and represents a significant improvement when compared to traditional FAB methods for contraception. This is the third study performed on Natural Cycles and is an important step towards substantiating clinical evidence around natural birth control methods.   In the study, 22,785 women, with an average age of 29 years, who use Natural Cycles for contraception, were observed to establish how many became pregnant within a year. The study analysed 224,563 menstrual cycles to calculate the Pearl Index for perfect and typical use of the application. The Pearl Index is a rate that summarizes how many women out of 100 may experience an unintended pregnancy within 1 year of using a contraceptive method.   Under perfect use, the app is 99% effective. Under typical use, the app is 93% effective - more effective than traditional FAB methods (with 75% effectiveness) and comparable to the contraceptive pill (with 91% effectiveness).   Natural Cycles, which is currently used by over 380,000 women worldwide,  works by recording the daily temperature under your tongue and inputting details about your menstrual cycle as well as data on urine luteal hormone, sexual activity and pregnancy. The advanced algorithm then pinpoints whether you are fertile on that day so you accurately know if and when to have protected intercourse (as such, the app is recommended for couples in a stable relationship where you are sure your partner is free from any STIs). The algorithm makes use of this data to detect ovulation and to predict future ovulation, and these predictions improve with time as users add more data.   Kristina Gemzell Danielsson, Professor, MD, PhD at the leading medical university Karolinska Institutet and Karolinska University Hospital in Sweden says "Since more and more women are choosing natural contraception as an option, we welcome that there is a certified app with solid clinical evidence."   James Trussell,  PhD,Professor emeritus at Princeton University and co-author of that publication says "This is the first study to provide typical- and perfect-use estimates of effectiveness of an app and shows the app is effective."   Dr Raoul Scherwitzl, co-founder of Natural Cycles says "The real life evidence collected in the largest study ever conducted on this method not only confirms the effectiveness of Natural Cycles but allows us to study how it is used in real life. It's a modern and innovative way of doing research that the industry wants to see more of."   Future research will be focused on studying acceptability among women by observing the impact of factors such as age, country of origin, social stratification, irregular menstrual cycles and dedication to the method.   Natural Cycles is available to download at www.naturalcycles.com, the App Store for iPhone, Apple Watch and iPad, and Google Play Store.   www.naturalcycles.com   ENDS Dr Elina Berglund (CTO) and Dr Raoul Scherwitzl (CEO) are available for interview. Media enquiries Harry Cymbler Hot Cherry harry@hotcherry.co.uk +44(0)20 7607 2413 +44(0) 7801 289 996   Notes *Results of the clinical study demonstrating the effectiveness of Natural Cycles as a natural birth control has recently been published in the peer-reviewed Contraception journal http://www.contraceptionjournal.org/article/S0010-7824(17)30429-8/pdf    About Natural Cycles www.naturalcycles.com Natural Cycles is the world's first, and only, app to be certified as a contraception in Europe. It can help women to prevent, plan and monitor pregnancies. Our mission is to educate and empower women to take control of their fertility and future, championing a vision where every pregnancy brings happiness. Natural Cycles has been shown in clinical studies to improve the use of natural family planning and be comparable to other forms of birth control. Natural Cycles was founded by husband and wife team Dr Raoul Scherwitzl and Dr Elina Berglund, a top physicist who was part of the Nobel Prize-winning team that discovered the Higgs boson. With PhDs in physics, they applied their mathematical techniques to create a unique algorithm which allows Natural Cycles to adapt to each woman's body individually. Natural Cycles app has over 380,000 users in 161 countries.

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PRESS RELEASE: One in ten owners are allergic to their animals - Vorwerk study

Media release   22 May 2017   One in ten pet owners is allergic to their furry friend • Nearly one in ten (8%) pet owners is allergic to their pet • 61% wouldn't consider giving up their pet because they love it too much • Half (48%) don't have any special cleaning measures to reduce the impact of their allergy • Tips on how to reduce pet allergens in the home   More than half of pet owners have admitted that they wouldn't consider giving up their animals even if they were allergic to it, a survey has revealed.   Following research by home appliance maker Vorwerk*, figures found that nearly one in ten (8%) pet owners were actually allergic to their furry friends.   However, 61% said they wouldn't lose their pet because of their allergies, whilst 53% saw their pets as part of the family.   Adding to the impact, almost half of households with allergies (48%) revealed that they did not have any special cleaning measures to reduce the impact of their allergy, making it worse for their loved ones.   Dr Jill Warner, Allergy expert and immunologist, said: "Pets are the second most important cause of domestic allergy, after the house dust mite. The allergens are found in the pet's dander, hair, saliva and urine.   "The cat allergen is very small so can quickly and easily spread, often settling in dust from floors and soft furnishings, in the air and even on walls. Dog allergens are larger particles which may be the reason why fewer people show allergic symptoms to dogs than they do to cats.   "Allergen control must be aimed at areas in the home where people spend most of their time and where allergen exposure is heaviest.  In practice this means applying special cleaning measures to the bedrooms and living room at a minimum."   Dr Jill Warner's top tips for an allergy free home Keep pets away from your bed. It's important to keep pets away from your bed to avoid them from spreading their allergens all over the area where you sleep.  Use allergen-proof barrier covers on all mattresses, duvets and pillows and wash your bedding regularly at at least 60 degrees.   Put soft toys in the freezer.  If your child is allergic to house dust mites put  soft toys in the freezer for 24 hours once a week to kill the mites . Wash the toy in the washing machine afterwards and leave to dry before allowing your child to play with it again.   Replace carpets with hard flooring. Replace your carpets with vinyl or wood flooring as these accumulate less allergens. If you have rugs in your home wash them regularly.     Vacuum regularly. Where carpets can't be removed, make sure you vacuum regularly along with vacuuming beds and soft furnishings.  It's important to use a high filtration vacuum cleaner which is able to collect and contain very small particles and clean a variety of surfaces such as the Kobold VK200 home cleaning system.   Decrease home humidity by increasing the ventilation. Try to keep your windows open and use extractor fans in kitchens and bathrooms to keep the house dry and ventilated. However if you are allergic to pollen windows should be closed during the grass and tree pollen seasons.   Cleaning expert Thomas Henningsson from Vorwerk added: "It's certainly no secret that the UK is a nation of pet lovers, but there are clearly a lot of people suffering so they can live with their furry friends.    "Our Kobold VK200 home cleaning system effectively removes allergens and pet hair, using filtering systems that deep clean your home. The VK200 uses a premium, three stage filter system which captures 99.99% of all dust particles and keeps them safely out of the air and inside the dust bag.  The multiple cleaning tools that it offers mean you can quickly and effectively clean pet hair and fur from all your carpets and soft furnishings."   For more information and tips on how to help keep your house clean when you have pets, please visit HERE.  -Ends- Notes to Editors For media enquiries, images, videos or interviews with the Vorwerk UK team, please email vorwerk@faith-pr.co.uk or call 01484 599 886.   *Research carried out by OnePoll among a nationally representative sample of 1,000 people between 20.03.2017-24.03.2017. OnePoll are members of ESOMAR and employ members of the MRS.    For more information about the Vorwerk Kobold VK200 vacuum cleaner, go to https://kobold.vorwerk.co.uk/home/   Follow Vorwerk UK on Twitter: @VorwerkUK Find Vorwerk UK on Facebook: Vorwerk UK   About Dr Jill Warner  Dr Jill Warner is an Honorary Professor at The University of Cape Town and was previously Reader in Allergy and Immunology in the Division of Medicine at Imperial College London. Dr Warner was also Head of Education for the Women and Children's Clinical Programme group at Imperial College Healthcare Trust from 2008-2011. She established the first UK Masters level course in Allergy at the University of Southampton in 2000 where she was the School of Medicine Co-ordinator of Taught Postgraduate Programmes and has subsequently established a new e-learning Postgraduate Certificate/MSc in Allergy at Imperial College that commenced in 2008 and for which she was the Course Director until 2016.   To request a media interview with Dr Jill Warner email vorwerk@faith-pr.co.uk     The history of Vorwerk  Vorwerk & Co. KG was founded in Wuppertal in 1883. During the course of its 130-year history, the company, originally a carpet factory, has grown into a highly diversified, global corporate group. Vorwerk nevertheless remains a family enterprise to this day.   Since 1930, Vorwerk's core business has been the direct selling of high-quality products. Divisions include Kobold, Thermomix, Twercs, Jafra Cosmetics, Lux, Vorwerk Flooring and akf bank. Superior products and a special customer approach are something all divisions have in common, and what makes Vorwerk so special.   Vorwerk has more than 12,000 employees worldwide and more than 600,000 sales people, and in 2015 generated a business volume totalling more than 3.4 billion euros with operations in 70 countries.   Vorwerk products have been available in the UK market for the last 30 years.

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The Femtech Revolution

Hi there,   Hope all's good. Do let me know if the following is of interest.    Tech is transforming every aspect of modern life for women, from wearable tech to fertility trackers. Now, for the first time, Dr Elina Berglund, who was part of the Nobel prize-winning team that discovered the Higgs boson, and now the co-founder of Natural Cycles the world's first and only app to be certified as a contraception, talks about the Femtech revolution and how it can flourish.   Full details and imagery below. Dr Elina Berglund is available for interviews so do let me know if you can run this.   Thanks Harry Founder, Hot Cherry harry@hotcherry.co.uk +44(0) 207 607 2413 +44(0) 7801 289 996   The Femtech revolution will flourish in 2017 but clinical evidence and changes in the regulatory framework are key, say Femtech pioneers     Tech is transforming almost every aspect of modern life for women and helping them acquire a deep insight into their body health - from fertility trackers to wearable health tech - but the Femtech revolution will only flourish when there is high quality, large-scale clinical data that demonstrates the product works, and when the regulatory framework can evolve to accommodate new trends, claim Femtech pioneers Natural Cycles who, in February 2017, became the world's first, and only, health app to be certified as a contraception for women with no side-effects.   "Femtech and, in particular, contraception is great for start-up businesses because pharmaceuticals have retracted from innovating in that space, which leaves a void that a new generation of entrepreneurs can fill and create sustainable businesses doing so", says Dr Elina Berglund, co-founder and CTO Natural Cycles, who was part of the Nobel prize-winning team that discovered the Higgs boson.   Three to four years ago Femtech did not exist, now you can use an app for contraception. Wearables are booming in the start-up sector and changing the way women interact with their bodies and self-manage their health. "Just like the boom in the fitness and health food industry women are seeking alternative ways that support their health values and body insight. Contraception has been at the forefront of feminism allowing women to make conscious decisions about their future, and Femtech is evolving this space", Dr Berglund adds.   There are barriers to the Femtech revolution, however, but these can be overcome. One major obstacle is the need for solid empirical evidence, underpinned by high quality and large-scale clinical data, to demonstrate that the product works. This point is significant and considered to be a vital asset for any brand working in Femtech. Sufficient resources need to be invested in high-quality clinical studies, which will serve as the basis for submission, approval, certification and marketing of a product. The review and approval of new Femtech products by regulatory agencies is dependent upon a trust that the clinical data presented has sufficient integrity to instil confidence and positive conclusions.   "Obtaining more research and large-scale clinical data to put a product on the market is critical to the success of the Femtech revolution", adds Dr Raoul Scherwitzl, co-founder of Natural Cycles. "The law must be able to evolve and adapt to placing Femtech products, like apps, within the regulatory framework, otherwise market access will be denied and tech innovation will stall - and that's problematic. In 2016 our large-scale clinical study* demonstrated that Natural Cycles was effective for contraception, yet the law was ambiguous as to how to go about regulating an app for contraception - the fundamental question was whether the app was a contraceptive or an information tool that advises users when to use contraception", he adds.   "If a product is not backed up by solid clinical data or medically regulated, e.g. has no valid CE mark, then it is not considered safe so why should women trust it?", asks Dr Berglund. "Trust is vital to tech innovation. We know we're dealing with women's lives here and we take that very seriously. It's proof to all women out there that properly regulated and certified tech, that is underpinned by quality clinical studies, is a valid choice - just as it is to take the pill every day or insert an IUD to prevent a pregnancy", she adds.                                                                                                                                                                                             The current Femtech space means that information, for example the data produced by Natural Cycles smart algorithm to inform women if they are fertile or not on a particular day, can have a similar impact or intended use as a drug.   As a result, the regulatory framework needs to evolve and adapt to this trend. "We're championing a Femtech world where tech could represents the next era in women's health", says Dr Berglund. "Tech & information is the future of women's health and contraception, but quality clinical studies and the evolution of a regulatory framework is paramount. Better insight means women can be empowered to take control and self-manage their health, fertility and future with more choice", she concludes.   The Femtech revolution will help to redress the number of women in tech, still hugely underrepresented in this sector (women made up 14.4% of the workforce in STEM industries in 2015) but interest amongst women for the products produced for them is increasing because women who understand the needs of these companies can identify with their products are, of course, more likely to work for that company. "It is a lot more fun to work for something you believe in, but there is a big gap to fill in the STEM sector and the Femtech revolution will make those positions more appealing to women", says Dr Berglund.   #NaturalCycles   ENDS Natural Cycles co-founders Dr Elina Berglund (CTO) and Dr Raoul Scherwitzl (CEO) are available for interview.   Media enquiries Harry Cymbler Hot Cherry harry@hotcherry.co.uk +44(0) 207 607 2413 +44(0) 7801 289 996   Notes *Results of the clinical study demonstrating the effectiveness of Natural Cycles as a natural birth control has recently been published in the peer-reviewed European Journal of Contraception & Reproductive Health Care http://ow.ly/10gLMr   Clinical Study: http://www.tandfonline.com/doi/full/10.3109/13625187.2014.988210    About Natural Cycles www.naturalcycles.com Natural Cycles is the world's first, and only, app to be certified as a contraception. It can help women to prevent, plan and monitor pregnancies. Our mission is to educate and empower women to take control of their fertility and future, championing a vision where every pregnancy brings happiness. Natural Cycles has been shown in clinical studies to improve the use of natural family planning and be similarly effective as the contraceptive pill. Natural Cycles was founded by husband and wife team Dr Raoul Scherwitzl and Dr Elina Berglund, a top physicist who was part of the Nobel Prize-winning team that discovered the Higgs boson. With PhDs in physics, they applied their mathematical techniques to create a unique algorithm which allows Natural Cycles to adapt to each woman's body individually. Natural Cycles app has over 200,000 users in 161 countries.

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Core Elementz: Achieving Epic Growth in Fitness Training

 

 

FOR IMMEDIATE RELEASE:

MEDIA CONTACT:  

Darius Coit

267-815-5719

managementbydarius@gmail.com

 

Core Elementz: Achieving Epic Growth in Fitness Training

Uptick in celebrity athlete endorsements assisting new company

 

Lakewood Ranch, FL (September, 2015) – Core Elementz, a subscription-based sports, fitness and nutrition company, has achieved an unprecedented amount of growth since its inception earlier this year. It has already made an impact in the lives of many successful professional athletes and is now focusing its outreach on the youth market and the general public.

 

“These programs can positively impact every client’s life, not only on a physical level, but through character development, empowering individuals to reach their goals and to educate them on proper training and techniques to help them develop their craft,” said Core Elementz Co-Founder Jason Riley.  He has been working as a professional sports trainer specializing in a holistic approach to training and nutrition to deliver exceptional performance on and off the field for all his clients.

 

Riley noted, however, that what Core Elementz has to offer is not limited to the already established pros. “We seek to improve the athletic capabilities of today’s youth, as well as promote quality of life for those that are no longer in athletics or just looking to improve their body composition, weight loss and focus on disease prevention,” he said.

 

Notable clients of Jason Riley include New York Yankee legend Derek Jeter, Major League Baseball All-Stars Ryan Zimmerman, Ryan Howard and Tyler Clippard, former NBA All-Stars Vince Carter and Chauncey Billups and tennis stars Maria Sharapova and John Isner, among others. Recently, Philadelphia Eagles’ tight end Trey Burton was featured in NFLSpinZone.com, where he credited Riley as well as the programs put together by Core Elementz to his offseason improvements.

 

The level of training and coaching for those athletes is the same that is provided to any other Core Elementz client, Riley added.

 

One particular priority in the ongoing client expansion efforts for Core Elementz is targeting today’s youth. According to a recent study, less than 5 percent of Americans enjoy ideal cardiovascular health and today’s teens have a shorter life expectancy than people of prior generations. Conversely, children who play sports are eight times more likely to be active as adults than those who do not play sports growing up.

 

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ABOUT CORE ELEMENTZ:

Founded in 2015 in Lakewood Ranch, FL, Core Elementz is the only online fitness and nutrition experience that offers its clients the same level of training as professional athletes. The company currently provides streaming video workouts, sports-specific skill, speed and strength training, 30-day meal and nutritional programs, all natural NSF Sports Certified supplements and a kid’s corner training section. Among the sports activities Core Elementz currently provides include soccer, baseball, football and MMA, and looks to expand into golf, tennis, basketball and  more in the very near future. For additional information or to become involved, go to www.CoreElementz.com

 

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Information presse : Tumeurs et métastases cérébrales - Chirurgie cérébrale sur patient éveillé, une opération en pleine évolution pratiquée par le Pr Metellus au sein de l'Hôpital privé Clairval, Marseille

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Bonjour,

 

Vous trouverez ci-joint une information presse de Ramsay Générale de Santé

 

 

TUMEURS ET MÉTASTASES CÉRÉBRALES

 

Chirurgie cérébrale sur patient évéillé

une opération en pleine évolution pratiquée par le Pr Metellus

au sein de l’Hôpital privé Clairval, Marseille

 

La chirurgie cérébrale sur patient éveillé, pratiquée par le Pr Philippe Metellus - Neurochirurgien au sein de l’Hôpital privé Clairval –, permet d’opérer des patients pour lesquels l’intervention chirurgicale était auparavant contre-indiquée. Engagé dans la lutte contre les tumeurs cérébrales, le Professeur est à l’origine de la conférence qui se tiendra les 2 et 3 octobre prochains sur la recherche et les thérapies émergentes dans la lutte contre les métastases cérébrales, à Marseille.

 

Une approche unique au monde initiée par le Pr Metellus au sein de l’Hôpital Privé Clairval

La chirurgie cérébrale sur patient éveillé est une approche innovante visant à déterminer les zones cérébrales à préserver durant une opération. Celle-ci permet ainsi d’opérer des patients dont la tumeur est située dans une zone sensible, proche des zones fonctionnelles du cerveau.

L’objectif est de faire appel au patient pendant son opération en sollicitant notamment la vue, le langage et la motricité pour ne pas retirer de zones essentielles. Une fois le patient réveillé, le chirurgien stimule les zones du cortex cérébrales sensibles proches de la lésion, en fonction de la réaction du patient, le chirurgien préservera ou non cette partie. Durant l’opération, le patient est entouré d’une équipe médicale complète (neurologue, orthophoniste, neuropsychologue…).

La cartographie per-opératoire, en condition éveillée, par stimulations électriques directes (SED) a depuis longtemps été validée en neurochirurgie dans la détection des zones fonctionnelles et constitue actuellement le standard dans ce type de prise en charge. Cependant l’exactitude des informations obtenues par cette technique reste sujette à caution car l’impact réel de la stimulation électrique directe corticale est mal connu. En effet, la possibilité de faux négatifs¹ ou de faux positifs² constitue un élément limitant à cette technique.

Pour augmenter la spécificité et la sensibilité de celle-ci, l’équipe du Pr Metellus et l’Hôpital privé Clairval ont mis en place un système d’enregistrement électrocorticographique permettant de visualiser en temps réel l’effet local et régional (64 électrodes permettant un échantillonnage spatial de 8 x 8 cm²) des stimulations électriques directes. Il est le premier établissement au monde à développer cette approche pionnière et innovante en chirurgie tumorale. 

 

« En réveillant le patient, on peut directement savoir si la zone que l’on souhaite opérer est essentielle. Il y a quelques années on ne pouvait rien pour ces patients. Grâce au système d’enregistrement électrocorticographique nous sommes aujourd’hui les premiers à proposer une approche aussi aboutie  », précise le Pr Philippe Metellus. 

 

5^ème édition de la Conférence sur la recherche et les thérapies émergentes dans la lutte contre les métastases cérébrales

Initiée et portée par le Pr Philippe cette conférence se tiendra les 2 et 3 octobre prochains à la Villa Méditerranée à Marseille. Depuis 5 ans, elle vise à faire avancer la recherche et les échanges sur ce sujet.

Placé sous l'égide de l'EORTC (European Association of Neurosurgical Societies) et du RTOG (Radiation Therapy Oncology Group), cet évènement majeur proposera entre autres cette année 3 workshop Europe/USA avec pour perspective de définir de nouveaux essais thérapeutiques et un focus particulier sera fait sur un thème majeur en oncologie : l'immunothérapie. A ce sujet d'ailleurs, le Professeur Kim MARGOLIN du Stanford Cancer Center tiendra une conférence sur ce thème.

A noter également que le Docteur Eskandari et le Pr Metellus animeront un symposium sur le CYBERKNIFE®,  robot articulé très mobile qui peut traiter une lésion même très petite, qu’elle soit fixe ou mobile, n’importe où dans le corps, et ce avec une précision infra millimétrique. Cette machine permet ainsi d’irradier des lésions proches d’organes à risque. Soulignons à ce sujet que l’Hôpital Privé Clairval à Marseille détient l’un des 8 CYBERKNIFE® « de dernière génération » disponibles en France.

Aux côtés de l'EORTC, du RTOG et de l'EANS (European Association of Neurosurgical Societies), le club -M- Ambassadeurs soutient cette conférence de même que la Région PACA, le Cancéropole PACA et Ramsay Générale de Santé.

 

Neurochirurgie oncologique : Recherche clinique et activité académique

Cette année, l’Hôpital Privé Clairval a été reconnu Etablissement EORTC (European Organization for Research and Treatment of Cancer) pouvant ainsi participer aux essais européens sur les tumeurs.

D’autre part, en collaboration avec le Dr Eskandari, radiothérapeute oncologue au sein de l’HP Clairval,  le Professeur Metellus a créé un institut de Neuro-Oncologie reconnu par les instances européennes et capable de recevoir des médecins en formation dans ce domaine.

Le projet de neurochirurgie oncologique proposé au sein de l’établissement positionne l’Hôpital privé Clairval en tant que structure clinique de pointe à dimension européenne, en mesure de proposer un programme de soin, d’enseignement et de recherche de pointe. 

 

« Nous avons intégré 2 essais nationaux sur les gliomes (CSA, BCB) et une attachée de recherche clinique travaille à plein temps sur les tumeurs cérébrales », souligne le Pr Metellus.

 

 

1 - Intensité de stimulation insuffisante du fait de l’hétérogénéité du seuil d’excitabilité des différentes régions corticales

2 - Propagation du courant électrique entrainant une désorganisation non plus focale mais loco-régionale ou à distance pouvant être responsable de la réponse clinique présentée par le patient

 

Bien cordialement,

 

Caroline Giry

Agence Bleu Ciel

04 91 19 16 16

bleuciel@societebleuciel.com

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